Franz Kuchling
Franz Kuchling is a co-author in Michael Levin's group on work spanning cancer electrophysiology, active inference models of morphogenesis, and collective resistance to teratogens in embryos123. Kuchling's other papers, on goal-directedness and intrinsic motivation, are cited in Levin's wider writing on minds of many kinds456.
- In the library
- 3 works, named in 4 passages elsewhere
- Facts from
- ORCID
Cancer and morphogenesis papers
The held methods describe patch-clamp chip recordings, in which hyperpolarization steps from −30 mV to −100 mV helped form the electrical seal1. Kuchling is also second author on a 2022 paper that treats active inference as a framework for action and perception, linked to psychiatric disorders and applied to morphogenesis2. In 2024, Kuchling co-authored the study of embryo groups, which found that larger groups resisted thioridazine-induced death and craniofacial defects. The authors named this the Cross-Embryo Morphogenetic Assistance effect3.
Cited on goal-directedness
Levin cites Kuchling et al. (2020a) in the TAME framework. The context is the claim that a minimal degree of internal self-determination and goal-directedness is apparently present even in particles, so there may be no true zero on the scale of consciousness4. Levin also cites Lyon and Kuchling (2021) in the argument that no sharp line separates systems that truly care from those that only perform5. A 2023 Levin review lists Kuchling et al. (2020) among work toward detecting and relating to natural, artificial and hybrid intelligences of any size or material6.
Acknowledged contributions
Biswas, Clawson and Levin (2022) thank Kuchling, with Juanita Mathews and Devon Davidian, for feedback on visualization in their paper on learning in transcriptional network models7. The held passages give no further detail on that contribution, and none shows a dispute over Kuchling's work.
After the capture, successive hyperpolarization steps from −30 mV to −100 mV were applied to foster the electrical seal formation.
Mathews J, Kuchling F, Baez-Nieto D, Diberardinis M, Pan…, 2022 · Ion Channel Drugs Suppress Cancer Phenotype in NG108-15 and U87 Cells: Toward… · open at passage 23Active inference is a computational framework for action and perception and has been linked to various psychiatric disorders (Montague et al., 2012).
Pio-Lopez L, Kuchling F, Tung A, Pezzulo G, Levin M, 2022 · Active inference, morphogenesis, and computational psychiatry · open at passage 12larger group size confers a significant protective effect against both thioridazine-induced death and craniofacial defects in a manner that cannot be explained by increased drug degradation in larger cohorts
Tung A, Sperry MM, Clawson W, Pavuluri A, Bulatao S, Yue M…, 2024 · Embryos assist morphogenesis of others through calcium and ATP signaling… · open at passage 12goal-directedness is apparently present even in particles (Feynman, 1942; Georgiev and Georgiev, 2002; Ogborn et al., 2006; Kaila and Annila, 2008; Ramstead et al., 2019; Kuchling et al., 2020a)
Levin M, 2022 · Technological Approach to Mind Everywhere: An Experimentally-Grounded Framework… · open at passage 105one view is that only biological, evolved forms have intrinsic motivation, while software AI agents are only faking it via functional performance
Levin M, 2022 · Technological Approach to Mind Everywhere: An Experimentally-Grounded Framework… · open at passage 25regardless of size scale or material implementation (Abramson and Levin 2021; Calvo et al. 2020; Fields et al. 2021; Fields and Levin 2022; Ginsburg and Jablonka 2021; Gokhale et al. 2021; Kuchling et al. 2020;
Levin M, 2023 · Bioelectric networks: the cognitive glue enabling evolutionary scaling from… · open at passage 10We thank Juanita Mathews, Franz Kuchling, and Devon Davidian for feedback on visualization.
Biswas S, Clawson W, Levin M, 2022 · Learning in Transcriptional Network Models: Computational Discovery of… · open at passage 67
2022
2022 · read
2022
2022 · read
2024
2024 · read