BioelectricaAlterspan Labs
JML
Person

Joan M Lemire

Joan Lemire is listed as a co-author on Xenopus work from Michael Levin's laboratory, including studies of HDAC inhibition in tail regeneration and of the embryonic brain's effect on distant muscle12. Papers from the same laboratory also thank Lemire for molecular biology and cloning assistance356.

Field
researcher
In the library
4 works, named in 7 passages elsewhere
Facts from
Wikidata · ORCID
18501875190019251950197520002025Tseng AS, Carneiro K, Lemire JM, Levin M, 20111Herrera-Rincon C, Herrera-Rincon C, Pai…, 20172Chernet BT, Levin M, 20143Pai VP, Vandenberg LN, Blackiston D…, 20124Paré JF, Martyniuk CJ, Levin M, 20175Pai VP, Cervera J, Mafe S, Willocq V…, 20206Herrera-Rincon C, Paré JF, Martyniuk…, 20207Morokuma J, Durant F, Williams KB…, 20178
01

Co-authored Xenopus results

The tail regeneration paper lists Lemire among its authors. It reported that the HDAC inhibitor trichostatin A at 25 nM, given after tail amputation, cut regeneration by 62% on the Regeneration Index1. The brain paper, which also lists Lemire, concluded that the early embryonic brain matters for muscle structure forming at considerable distance2. The passages do not say which experiments Lemire carried out, so the individual contribution cannot be stated here.

02

Laboratory and molecular support

Acknowledgments from 2012 to 2020 name Lemire. A 2012 paper on neurally derived tissues thanks Lemire for Xenopus husbandry and general lab assistance4. A 2014 paper thanks Lemire, with Jean-Francois Pare, for molecular biology assistance3. Later papers repeat the thanks for molecular biology57. A 2020 paper on HCN2 channels thanks Lemire for cloning cDNAs into injection vectors6. Across these papers the role named most often is molecular biology.

03

A planarian citation

A 2017 paper on planarian regeneration in space cites a 2013 paper by Beane, Morokuma, Lemire and Levin. It places that paper among work linking bioelectric physiology to morphology in planarians8. The passage does not describe the 2013 paper's findings. It also does not say whether this Lemire is the same person, so the link is noted only as a possible one.

SourcesEach quotation was checked word for word against the passage it opens.
  1. treatment with 25 nM TSA after tail amputation specifically inhibited regeneration (a decrease of 62% as determined by the Regeneration Index (RI)Tseng AS, Carneiro K, Lemire JM, Levin M, 2011 · HDAC activity is required during Xenopus tail regeneration · open at passage 12
  2. Taken together, these results clearly indicate the importance of the early embryonic brain for normal development of muscle structure occurring at considerable distance.Herrera-Rincon C, Herrera-Rincon C, Pai VP, Moran KM…, 2017 · The brain is required for normal muscle and nerve patterning during early… · open at passage 12
  3. We thank Amber Currier, Erin Switzer, and Amanda Allen for general lab assistance and frog husbandry, and Joan Lemire and Jean-Francois Pare for molecular biology assistance.Chernet BT, Levin M, 2014 · Transmembrane voltage potential of somatic cells controls oncogene-mediated… · open at passage 45
  4. The authors thank Punita Koustubhan, Amber Currier, Joan Lemire, and Claire Stevenson for Xenopus husbandry and general lab assistancePai VP, Vandenberg LN, Blackiston D, Levin M, 2012 · Neurally Derived Tissues in Xenopus laevis Embryos Exhibit a Consistent… · open at passage 41
  5. Joan Lemire for assistance with molecular biology; Joshua Finkelstein for useful comments on the manuscriptParé JF, Martyniuk CJ, Levin M, 2017 · Bioelectric regulation of innate immune system function in regenerating and… · open at passage 55
  6. We thank Jean-Francois Pare and Joan Lemire for assistance with the cloning of cDNAs into injection vectors PCS2.Pai VP, Cervera J, Mafe S, Willocq V, Lederer EK, Levin M, 2020 · HCN2 Channel-Induced Rescue of Brain Teratogenesis via Local and Long-Range… · open at passage 56
  7. Joan Lemire for assistance with molecular biology; Vikas Trivedi and Todd Chappell for assistance with E. coli preparationHerrera-Rincon C, Paré JF, Martyniuk CJ, Jannetty SK…, 2020 · An in vivo brain-bacteria interface: the developing brain as a key regulator of… · open at passage 70
  8. polarity (Beane, Morokuma, Adams, & Levin, 2011), and morphology (Beane, Morokuma, Lemire, & Levin, 2013Morokuma J, Durant F, Williams KB, Finkelstein JM…, 2017 · Planarian regeneration in space: Persistent anatomical, behavioral, and… · open at passage 3
In the library4 works
Histone deacetylase activity is necessary for left-right patterning during vertebrate developmentCarneiro K, Donnet C, Rejtar T…
2011
Histone deacetylase activity is necessary for left-right patterning during…
Carneiro K, Donnet C, Rejtar…
2011 · read
HDAC activity is required during Xenopus tail regenerationTseng AS, Carneiro K, Lemire JM…
2011
HDAC activity is required during Xenopus tail regeneration
Tseng AS, Carneiro K, Lemire…
2011 · read
The brain is required for normal muscle and nerve patterning during early Xenopus developmentHerrera-Rincon C, Herrera-Rincon…
2017
The brain is required for normal muscle and nerve patterning during early…
Herrera-Rincon C…
2017 · read
HCN4 ion channel function is required for early events that regulate anatomical left-right patterning in a nodal and…Pai VP, Willocq V, Pitcairn EJ…
2017
HCN4 ion channel function is required for early events that regulate anatomical…
Pai VP, Willocq V, Pitcairn…
2017 · read
Quoted inArticles that quote this person's work