Revisiting the mitogenetic effect of ultra-weak photon emission

We strongly recommend careful inquiry of methodical recommendations in Rahn (1936), Gurwitsch and Gurwitsch (1945) for any research in this topic.

In general, investigating biological processes by means of their external stimulation is quite a difficult and dubious way. A much more powerful tool of the present day research is inhibitory analysis (in broad sense). This approach is likely to be more effective than numerous attempts to stimulate cell division. Thus, it should (and can be) also applied to this area. At present time, a large set of agents inhibiting or screening radiation are available and their usage can elucidate a disputable question on the biological role of endogenous photon emission.

In our opinion, a promising way of working with MGE would be to suppress internal mitogenetic stimulation in the system, and then stimulate cell division in it by external inductors of MGE. It is certainly complicated to figure out an agent, specifically suppressing MGE without any toxic effect. But first, there is some information available on this topic (Gurwitsch and Gurwitsch, 1959; Gurwitsch, 1968), and second, it might be the most vivid method of addressing the effect.

Next, it might be reasonable to temporally leave apart the biological effect and concentrate on physical measuring devices, which have been greatly improved since Gurwitsch's times. This means also that we have to abandon, at least for some time, detailed spectral analysis of the radiation, which was based almost exclusively on “biological detectors.” What may be suggested instead, is analysis of frequency spectra (Fourier or wavelet), which may be obtained with modern technique within a wide range of characteristic times. As shown by tentative experiments (Beloussov, 2002, 2006; Volodyaev and Beloussov, 2007), such analysis reveals a definite radiation component in the responses of cells to the action of various non-specific stresses (Figure 5), cytoskeletal inhibitors and growth factors (Figure 6). The latter is of a special interest, because it confirms connections between photon emission and induction of cell division (performed in these experiments by chemical agents).

In addition, Fourier analysis permitted to observe the radiation component in the crucial developmental event, known as mid-blastula transition and associated with the burst of embryonic genes activation (Figure 7). In any case, detection of the optical range energies obeying regular temporal patterns greatly enriches our view upon cell signaling, gene expression and the function of cytoskeletal components.

It is also unpardonable to ignore mitogenetic data on cancer pathologies. We must definitely know whether the “cancer quencher” claimed by a number of authors, really exists in blood of cancer patients, and what role in the development of the disease it might play.

And the last, but definitely not the least. Physical measure of UPE cannot give any information about its biological role (if there is any). A fully parallel research of biological MGE and UPE from the same objects, and most important, under identical conditions (including temperature, light, aeration, etc…) should be done, if a good and stable biological effect is obtained. This could be a breakthrough for understanding the mechanisms of both sending and receiving the “MGE signal.”

The authors' view is that research on MGE should be renewed with the use of the entire set of powerful approaches acquired by modern science.

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.