Impact

What it takes to
reach more people.

Easier delivery could bring vaccination closer to people who miss it today. We are developing patches with that goal—and studying what it would cost to reach them.

Worldwide · 2025

19.5 millionchildren without a full
DTP vaccine course.

Three doses are needed to complete the routine course.

Children missing DTP dosesWorldwide · 2025
13.5 million children received no first dose; another 6 million were partially vaccinated. Thirty-nine child symbols, each representing 500,000 children. Twenty-seven brown symbols represent children without a first DTP dose. Twelve green symbols represent children who started but did not receive all three doses.
Each symbol represents 500,000 children.
No first dose
13.5 million
Partially vaccinated
6 million

Global estimates for 2025. DTP protects against diphtheria, tetanus and pertussis.WHO / UNICEF

Reach further.

Make vaccination more practical where storage and transport limit access.

Miss fewer opportunities.

A single-dose patch could make small outreach sessions easier to run.

Use health workers’ time well.

Test whether simpler preparation and application leave more time for care.

Illustrative scenario · one vaccine dose per person
1,000,000
80%
85%

Change coverage to explore additional reach. This is an assumption, not a forecast.

Cost assumptions

MR vaccine: $0.82/dose · Assumed patch: $1.75.

$2.34
UNICEF 2024: $2.34; uncertainty $0.80–$5.47.
30%
$0.93
Purchase-price difference, not manufacturing cost.
$0.00
Added for each additional person reached.

Additional people vaccinated

50,000
Currently800,000 · 80%
With patches850,000 · 85%

Annual vaccine + delivery cost

Current approach
$2,528,000
With patches
$2,879,800
Added annual cost
$351,800
Added cost / additional person vaccinated
$7.04

Includes the cost of switching existing doses and vaccinating additional people.

Coverage and cost changes are assumptions. The starting patch price is $1.75, including a $0.93 premium. All costs use 2024 US dollars.

How the calculator works +

One selected vaccination. This scenario counts people receiving one selected dose each year, not people completing a full vaccination schedule or becoming protected. Measles–rubella (MR) is the price reference. Other vaccines and populations need their own inputs.

Current approach: people currently vaccinated × ($0.82 vaccine price + current delivery cost). With patches: people vaccinated with patches × ($0.82 + product-price premium + reduced delivery cost), plus any extra outreach cost for additional people.

Reach further applies patches to both the existing vaccinations and the additional vaccinations. Added cost per additional person is the total cost difference divided by additional people vaccinated. When there is no additional reach, this ratio is not defined. Same coverage keeps the number of people vaccinated unchanged.

The starting $1.75 patch price, 30% delivery-cost reduction and 80% → 85% coverage are illustrative assumptions, not an Alterspan quotation, measured performance or a prediction. By default, delivery has the same unit cost for existing and newly reached people; the extra outreach input lets you increase the latter.

This is a selected-vaccination cost comparison, not a full programme budget or a disease-impact model. It excludes wastage, differences in injection supplies and procurement fees, transition costs and avoided illness. Economic savings may represent staff capacity rather than money released from a budget.

Vaccine and delivery inputs: UNICEF, 2024.

01 / One child

Delivery is more than half the cost.

A reference childhood schedule, before changing how any vaccine is delivered.

Cost per fully vaccinated child$73.15Under 24 months · 2024 US dollars
$31.12Vaccines & injection supplies
$42.03Delivery · 57% of the total

UNICEF’s reference for countries procuring through UNICEF at Gavi-eligible prices. This is a fundraising benchmark; local programme costs vary.

Source: UNICEF, 2024.

Reading the source totals +

The figure uses the report’s combined commodity subtotal, $31.12, plus delivery, $42.03. Its separately displayed vaccine and injection-supply values ($30.29 and $0.76) sum to $31.05. We retain the published combined subtotal without inventing an explanation for that difference.

The report’s $42.03 delivery subtotal also differs from 18 × the rounded $2.34 unit cost ($42.12). The scenario calculator uses the unit cost entered above; the reference figure reproduces the published schedule total.

02 / Delivery

What delivery pays for.

The people and systems behind each vaccination.

Getting vaccines
to people.

Health workers and training.
Travel, transport and storage.
Waste collection and disposal.

Running the
programme.

Planning and local facilities.
Community engagement.
Disease and safety monitoring.

Full cost breakdown +

Where a patch could change delivery

  • Health workers
  • Per diems and travel
  • Cold-chain equipment
  • Vehicles, transport and fuel
  • Training and capacity building
  • Waste management

Effects depend on stability, application requirements and the delivery setting. A new presentation can also introduce costs.

Still part of an immunisation programme

  • Programme management
  • Social mobilisation and advocacy
  • Buildings, utilities and shared costs
  • Disease surveillance
  • Adverse-event monitoring

Changing the presentation does not remove the need to run, monitor and support the programme.

Eleven cost categories from UNICEF, 2024. The grouping is Alterspan’s research hypothesis, not a measured cost reduction.

03 / Wastage

Presentation changes the losses.

Selected planning assumptions from UNICEF’s reference schedule. Vaccine, vial size and delivery setting all matter.

Vaccine presentationPlanned wastage · common scale, 0–60%
1 doseRotavirus; HPV
3%
2 doses / vialMalaria
10%
4 doses / vialPneumococcal
17%
5 doses / vialJapanese encephalitis
30%
10 doses / vialPolio, pentavalent, measles–rubella
32%
10 doses / vialTyphoid conjugate
20%
20 doses / vialBCG
54%
A single-dose presentation avoids leftover doses in an opened multidose vial. The 3% figure belongs to the source examples; patch wastage remains to be measured.

Planning assumptions: UNICEF, 2024.

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