Research
Work in
the open.
Studies, methods and reading from our work on delivery, tissue and cellular response.
Bioinspired delivery
Biological mechanisms and patch design
Design analysis
Biological puncture and the dissolving patch
Five biological puncture mechanisms, their constraints, and what they can teach us about a dissolving vaccine patch.
Tissue Models
Tissue culture and recovery measurements
Research note
Human skin culture and dose recovery
What human skin studies can tell us about delivery, activity and local response.
Measurement note
Measuring recovery after a perturbation
Depth of response, time to recover and the change remaining at the end of observation.
Cellular regulation
Expression, molecular interactions and functional response
Expression reanalysis
GHK: repair, fibrosis and ageing
Two expression hypotheses, tested against public data. Neither is confirmed by this pilot.
Computational study
Epitalon sequence specificity in chromatin context
The same four amino acids, in 24 orders. The predicted preference reverses between histone contexts.
Data diagnostic
Checking cell-expression data
Five untreated cell records reveal gene entries missing from a model’s input vocabulary.
Evidence reanalysis · supporting study
Pinealon: auditing the performance claims
What remains when the arithmetic, controls and source figures are checked.
Mechanistic modelling · supporting study
The Energetics of Actoprotection
A conditional test of energy cost and preserved function in electrical models.
Libraries & publishing
Immunisation off the grid.
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